Driving Directions from Buffalo to St. Louis

Road trip starts at Buffalo, US and ends at St. Louis, US.

Trip (742.5 mi) Route Directions: Buffalo » St. Louis

Your directions start from Buffalo, NY, USA and end at St. Louis, MO, USA.

Like the driving directions from Buffalo to St. Louis? Need more details on the distances between these two locations? See the chart which displays detailed distance from Buffalo to St. Louis.

Or maybe you'd like to see a more detailed driving directions map? One is available which provides satellite imagery on the road map from Buffalo to St. Louis.

Calculating the travel time to St. Louis is as important as knowing how to get there. So take a look at the travel time from Buffalo to St. Louis.

Did you know that you can also calculate the time it takes to fly to St. Louis? Take a look at the flight time from Buffalo to St. Louis.

While flying may be quicker, it's always more cost efficient to drive to your destination so you may want to calculate the fuel cost from Buffalo to St. Louis.

Additionally areas of St. Louis might be highly elevated which can make it more difficult to drive there... How elevated? See the route elevation from Buffalo to St. Louis.

Still want more flight details? See the flight distance from Buffalo to St. Louis.

* Due to road conditions, road work and other unpredictable conditions, these directions should be taken as estimates.